Caffeine and headache: specific remarks.
نویسندگان
چکیده
Caffeine is the most widely used psychostimulant worldwide. Excessive caffeine consumption induces a series of both acute and chronic biological and physiological changes that may give rise to cognitive decline, depression, fatigue, insomnia, cardiovascular changes, and headache. Chronic consumption of caffeine promotes a pro-nociceptive state of cortical hyperexcitability that can intensify a primary headache or trigger a headache due to excessive analgesic use. This review offers an in-depth analysis of the physiological mechanisms of caffeine and its relationship with headache.
منابع مشابه
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عنوان ژورنال:
- Neurologia
دوره 32 6 شماره
صفحات -
تاریخ انتشار 2017